About Us

Trusted Dental Care in Sikeston, MO

At Cox Family Dentistry, we’re more than just a dental office—we’re a compassionate, community-centered practice rooted in Sikeston, Missouri. Led by Dr. Sam Cox, our mission is to provide exceptional, innovative dental care while creating meaningful experiences built on compassion, connection, and clinical excellence.

We believe that great dentistry starts with genuine relationships and a commitment to helping people live healthier, more confident lives.

Meet Dr. Sam Cox

Born and raised in Sikeston, Dr. Sam Cox is proud to serve the community he’s always called home. He earned his undergraduate degree in Biomedical Sciences from Southeast Missouri State University and completed his Doctor of Dental Surgery (DDS) at Creighton University. Driven by a lifelong passion for science and helping others, Dr. Cox found the perfect balance of precision, creativity, and personal connection in dentistry.

As a dedicated lifelong learner, Dr. Cox continues to advance his skills through study clubs, continuing education, and mentorship. He’s committed to staying at the forefront of modern dental techniques to deliver care his patients can trust.

When he’s not caring for patients, you’ll find Dr. Cox enjoying the outdoors—hunting, fishing, and cheering on his favorite sports teams.

Our Philosophy: Compassion. Connection. Confidence.

We understand that visiting the dentist can be stressful for many people. That’s why we’ve built an environment where patients feel safe, respected, and fully informed about their care. Dr. Cox and our team take the time to listen, answer questions, and explain every treatment option—without pressure or judgment.

We don’t just treat teeth; we care for the whole person. Our goal is to help you feel confident in your smile and in your experience with us—every step of the way.

Why Patients Choose Cox Family Dentistry

Locally Owned & Operated in Sikeston, MO

Friendly, Judgment-Free Dental Care

Advanced Training & Modern Techniques

Personalized Treatment Plans

Strong Emphasis on Patient Comfort & Communication

Financial Impormation

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What Patients Are Saying!

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Our 5-Star Rated Dental Practice

Friendly, judgment-free dental care with advanced general, cosmetic, and restorative services – all designed to keep you smiling.